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Its ability to stimulate GH release without affecting other endocrine axes makes it a highly targeted and reliable peptide for research into hormonal modulation and peptide-based growth factor regulation

At this point, we have previously shown that IGF-I is a main character in restoring mitochondrial dysfunction during aging by increasing mitochondrial membrane potential, reducing oxygen consumption, and increasing ATP synthesis what in turn minimize the c-cytochrome release to the cytoplasm and subsequently promote neural survival by decreasing caspase-induced apoptosis[55, 56], in agreement with in vitro reported works from others[242244]

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The antitumor activity of CHE has been demonstrated in in vitro experiments for cytotoxicity and growth delay against various tumor cell lines (Malikova et al., 2006)

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