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This eventually prevents mitochondrial damage and the cytosolic release of oxidized mtDNA, a direct activator of NLRP3, limiting the processing of mature IL-1 69

Western blot assay K7M2 cells were incubated with the PBS, Ru(II)-OH, NP2, or NP4 (10 M Ru) for 12 h at 37 C, and the supernatant was subsequently co-incubated with RAW264.7 cells

Infections of the hypothalamic-pituitary region, in: Endotext (2021)

Geng HX, Wang L (2019) Cadmium: toxic effects on placental and embryonic development

Human iPSCs derived astrocytes rescue rotenone-induced mitochondrial dysfunction and dopaminergic neurodegeneration in vitro by donating functional mitochondria

Luc, JG, Fowler, CS, Eisenberg, SB, Estrera, AL, Wolf, RK, Choi, CW, Lawton, JS, Martin, LW, Nesbitt, JC, Reznik, S, Nguyen, TC, Vaporciyan, AA, Antonoff, MB