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doi: 10.1016/j.bjoms.2009.08.001

A unique gain factor is then calculated for each sample (represented by a scalar multiplier k) and compound ion abundances were adjusted to a normalization reference run 68

The overall response (OR) was 13.9%

Simmonds P, Holmes EC, Cha TA, Chan SW, McOmish F, et al

77 In summary, rRNA modifications are integral to regulating translation efficiency, optimizing protein synthesis, and affecting the growth of organisms as well as the onset of diseases