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One key receptor is retinoic acid-related orphan receptor-alpha (RORA), which was shown to be reduced in individuals with ASD

Werth VP, Culton DA, Concha JSS, Graydon JS, Blumberg LJ, Okawa J, et al

This risk has not yet been confirmed in animal studies, but long-term human data do not exist

150 T2DM and Gastroesophageal Reflux Disease (GORD) Commonly, the T2DM population has an increased BMI which is well recognised to be associated with symptoms of GORD