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Glutathione supplementation to university of Wisconsin solution causes endothelial dysfunction

doi: 10.1093/emboj/18.5.1321

For IV glutathione injections, dosage is calculated by body weight, typically 10-20mg per kg, because IV bypasses digestion and enters the bloodstream directly at near 100% absorption

50 Spontaneous intramolecular rearrangement and elimination of the carbamate group at C10 of mitomycin C results in a second alkylation reaction with the opposite strand of DNA to induce cytotoxic 1,2-GG interstrand crosslink lesions (Figure 7)

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