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(Kraus et al., 2014) shed light on NNMTs regulation of energy metabolism and associated mechanisms through laboratory experiments

Ruttmann E, Brant LJ, Concin H, Diem G, Rapp K, Ulmer H, et al

Boosts Metabolic Efficiency 5-Amino-1MQ may improve metabolic efficiency by inhibiting the enzyme nicotinamide N-methyltransferase (NNMT), which regulates energy metabolism

Specifically, the ability of vitamin C to scavenge free radicals can reduce the degree of oxidative stress and increase the viability of nerve cells in the cerebral cortex and striatum (Ballaz and Rebec, 2019)

Evaluation of the pro-oxidant and antioxidant actions of L-DOPA and dopamine in vitro: implications for Parkinson's disease