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While it doesnt act on the vascular system in the same way as PDE5 inhibitors, caution is still advised

CrossRef Metabolic Dysfunction-Associated Steatotic Liver Disease in Type 2 Diabetes Mellitus: A Review and Position Statement of the Fatty Liver Research Group of the Korean Diabetes Association Jaehyun Bae, Eugene Han, Hye Won Lee, Cheol-Young Park, Choon Hee Chung, Dae Ho Lee, Eun-Hee Cho, Eun-Jung Rhee, Ji Hee Yu, Ji Hyun Park, Ji-Cheol Bae, Jung Hwan Park, Kyung Mook Choi, Kyung-Soo Kim, Mi Hae Seo, Minyoung Lee, Nan-Hee Kim, So Hun Kim, Won- Diabetes & Metabolism Journal.2024

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Therefore, the elevated release of pro-inflammatory cytokines by senescence adipocytes possibly leads to the elevated risk of the cytokine storm in COVID-19 infection in poor prognosis patients

Overall, resveratrol exerts multi-faceted anti-cancer effects by modulating tumor immunity (e.g., boosting cytotoxic T cells and NK cells), reversing drug resistance (via down-regulating EGFR and P-gp), inducing autophagy and ferroptosis, and arresting cell cycle progression while promoting apoptosis