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In addition, studies have found that TMAO increases NADPH oxidase activity, induces the production of ROS, and an increase in ROS can promote the translocation of NF-B from the cytoplasm to the nucleus (68)

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Engineering live cell surfaces with functional polymers via cytocompatible controlled radical polymerization

Therefore, during the reperfusion experiments, the heart vasculature of the rats was exposed both to intact GSNO and to constant NO fluxes of 3.45 0.001 nmol mL min and 8.20 0.006 nmol mL min, arising from GSNO decomposition in the 200 M and 500 M reperfusion solutions, respectively

history of chemotherapy, radiotherapy, or head and neck malignancy involving the oral cavity