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In recent years, epidemiological and translational medicine research has continually revealed how air pollution, heavy metals, and various chemicals affect gut health through multiple mechanisms, promoting the onset and exacerbation of IBD

Inflammatory signaling is intricately linked with oxidative stress, where DAMPs released from injured ovarian cells activate TLR4 and downstream NF-B and NLRP3 inflammasome pathways

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In the same study, Sharon et al

Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are very important incretin hormones

Rumack BH, Peterson RC, Kock GG, et al