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We detected significantly reduced XBP1 levels at both time points although the reduction in XBP1 levels was relatively less at the later point likely due to significant and progressive decline of XBP1 expression in -cells of wild-type NOD mice prior to diabetes onset 5,35

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3.3.2 Metabolic regulatory functions of short-chain fatty acids (SCFAs) As the primary fermentation products of dietary fiber, SCFAs serve as core mediators of communication between gut microbiota and host metabolism

Recent advancements in fatty acid acylation-based protraction technology have provided the possibility of achieving extended plasma half-lives without increasing molecular size, leading to the discovery of semaglutide, a GLP-1 analog with a t