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Opioid and monoaminergic receptor binding Primary molecular targets of kratom alkaloids have been characterized using in vitro receptor-binding and functional assays in HEK293 and CHO cells expressing human opioid, adrenergic, and serotonergic receptors under acute, assay-dependent exposure conditions

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[DOI] [PMC free article] [PubMed] [Google Scholar] 124.Fukuda N, Toda K, Fujiwara YU, Wang X, Ohmoto A, et al