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Ultra-High Content and Concentration

10.1021/acsomega.2c07297 14 CaoH.XiaoJ.LiuH

Effect of high-dose N-acetylcysteine on exacerbations and lung function in patients with mild-to-moderate COPD: a double-blind, parallel group, multicentre randomised clinical trial

However, these effects are gradual and vary between individuals

PMC 2064426

In PVL patients, oligodendrocyte death is closely associated with iron accumulation, excessive lipid peroxidation, and elevated levels of ROS, MDA, and non-transferrin-bound iron in the CSF (395), providing a compelling rationale for targeting ferroptosis in disease management