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Corneal and conjunctival drug permeability: systematic comparison and pharmacokinetic impact in the eye

To get a sense of the uncertainty in the BAC estimate play around with the parameters (especially the alcohol elimination rate) and see how much your BAC curve changes

While not listed as a direct adverse effect in FDA prescribing information, this cold sensitivity appears linked to the medication's weight loss effects rather than direct temperature regulation changes

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Call your doctor: If you experience any of these rare side effects and they don't go away or get worse, it's important to call your doctor for further evaluation

However, practices without negotiated contracts receive significantly lower out-of-network reimbursement, often 40-60% of standard Medicare allowances