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However, translating these mechanistic insights into clinical benefit is hindered by three interconnected challenges, each of which offers critical directions for future investigation

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RecA binds single stranded DNA, eliciting transcriptional changes that can inhibit proper cell division 31

3D) was elevated in the PXN HIGH and CAF HIGH groups compared to PXN LOW and control (group age interaction and pairwise comparisons

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Homeostasis restoration was accompanied by a 2.0-2.4-fold decrease in acute respiratory disease incidence, reduced incidence of the clinical manifestations of ischemic heart disease, hypertension disease, deforming osteoarthrosis and osteoporosis as compared to the control