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Additionally, MetS refers to a group of metabolic anomalies linked to visceral fat accumulation

Cytom Part A 85(8):729737 Pisonero-Vaquero S, Medina DL (2017) Lysosomotropic drugs: pharmacological tools to study lysosomal function

These signal within the brain and nervous system to influence things such as mood, appetite and pain growth factors (IGF-1)

B12 deficiency can cause fatigue and poor metabolism, which can be the cause of your sudden weight gain

therefore, there is not enough data on the potential long-term effects on the endocrine system and neurological function