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J., 2014, vol

1 Remove Epithalon vial from refrigeration and allow to reach room temperature (1520 minutes) 2 Clean vial top with alcohol swab and allow to air dry completely 3 Using a sterile syringe, draw the calculated volume of bacteriostatic water (BAC water) 4 Inject BAC water slowly down the side of the vial do not aim directly at the powder 5 Gently swirl in circular motions DO NOT shake vigorously as this degrades the peptide 6 Allow 23 minutes for full dissolution solution should be clear and colorless 7 Draw calculated dose into an insulin syringe for subcutaneous injection 8 Inject into abdomen, thigh, or upper arm

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It was originally isolated from human plasma in 1973 and has since become one of the most widely researched copper peptides in published scientific literature

While injections are the commonly preferred method for administering peptides, nasal spray may be a comparable method of delivering DSIP

For in vivo pharmacokinetic analysis, male Sprague-Dawley rats weighing 250 g were cannulated in the right jugular vein