chac1 glutathione Dysregulated lipids homeostasis disrupts CHAC1-mediated ferroptosis driving fibroblast growth factor receptor tyrosine kinase inhibitor AZD4547 resistance in gastric cancer Calcium channel mutants rescue the
Calcium channel mutants rescue the effect of glutathione depletion. (A) Download Scientific Diagram CHAC1 inactivation is effective to preserve muscle glutathione but is insufficient to protect against muscle wasting in cachexia PLOS One Mammalian proapoptotic factor ChaC1 and its homologues function as glutamyl cyclotransferases acting specifically on glutathione EMBO Reports Springer Nature Link A scheme of the mechanism of CHAC1 degradation of glutathione enhancing Download Scientific Diagram The CHAC1 inhibited Notch3 pathway is involved in temozolomide induced glioma cytotoxicity ScienceDirect CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers PMC
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