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This mitochondrial dysfunction was accompanied by abnormal morphology of the brain mitochondria, and reduced synaptic density [382]

Glimma was used for interactive visualizations

TABLE 2 Patients demographics

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Quantitative PCR (qPCR) was performed using Real-time quantitative PCR kit (TaKaRa, Japan) and an LightCycler 96 system (Roche, Switzerland)