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10.1016/j.jtho.2021.01.141 48 GridelliC.CiuleanuT.DomineM.SzczesnaA.BoverI.CoboM.et al (2020)

The good news is GLP-1s are becoming more available with new oral preparations commercially availability

When NNMT activity is high, less nicotinamide is available for NAD+ synthesis

Adequate B1 supports peripheral nerve function and prevents complications of deficiency, such as neuropathy and Wernicke-Korsakoff syndrome in severe cases