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In another study, curcumin increased the expression of the small non-coding RNA miR181b, which then downregulated proinflammatory cytokines , CXCL1 and CXCL2, as well as MMPs, thereby reducing the metastatic potential of breast cancer cells

10.1038/s41418-020-00728-1 21 ChenY.LiuS.LiJ.LiZ.QuanJ.LiuX.et al (2020)

During the procedure, underlying connective tissue is reinforced to improve support and contour