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Glutathione analysis and quantification in Korean supplements: method development and validation

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A high toxic pressure of Cpz has been confirmed in fish plasma models, with a concentration of 36 ng L 1 corresponding to critical environmental concentrations (CEC) ( Mytilus galloprovincialis , Cpz inhibited metamorphosis by 50% (IC) at a concentration of 1.6 10 M ( Brachionus calyciflorus , known for its higher sensitivity to drugs compared to other invertebrates, exposure to Cpz significantly decreased life expectancy at hatching, the net reproduction rate, generation time, population growth rate, and dopamine concentration

10.1016/j.intimp.2021.108090 14 DesmondP

[PubMed: 19942075] (Letter in response to Yarema [2009] questioning whether AST elevations should be used as an endpoint in assessing efficacy of N-acetylcysteine regimens)

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