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Non-clinical test systems there is a need to develop more relevant human-derived in vitro systems to improve the assessment of cMRTPs and gradually replace in vivo rodent models

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Commenting on the research, lead author Dr Chantal Donovan, from Monash University in Victoria, Australia, said: By understanding the mechanisms responsible for reduced sensitivity to current bronchodilators, we can then design alternative, more efficacious agents to help treat people with COPD, especially during a viral exacerbation

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