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Methylene blue is an oxidant that is reduced by NADPH to its active metabolite, leukomethylene blue

10.1523/JNEUROSCI.17-03-00932.1997 206 SweeneyP.QiY.XuZ.YangY

When cutting a part of the root tip not exceeding critical size determined by the root thickness, the root is capable of forming a new root cap and quiescent center, and the same root can be decapitated repeatedly [13, 14]

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PLOS ONE 10 , e0142347 (2015)