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Disturbed and ecologically dysfunctional intestinal flora is a typical feature of IBD, where butyrate-producing bacteria (e.g., Faecalibacterium , Roseburia hominis , and Bifidobacterium ) are in lower abundance, resulting in reduced butyrate levels (247, 248)

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Clinical trial results: Cagrilintide weight loss data Real-world evidence from rigorous studies

Accumulation of lactate further supports metabolic flexibility and promotes an immunosuppressive microenvironment

These interventions are most effective when started at least 90 days before conception attempts

PMID: 29740811