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159 It also appears to modulate the gut microbiome in part through its effects on immune signaling

Metabolic labelling of MCF7 cells expressing GSTP1_4XCysAla/Lys103Arg mutant retains palmitoylation Our LC-MS/MS results showed that GSTP1 palmitoylation in vitro can occur on at least amino acids Cys48, Cys102, and Lys103, and these sites are candidates for palmitoylation in cells

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Clinical experience and limited human data suggest daily doses between 200-1000 g, with 500 g representing a commonly reported effective dose, though these figures lack rigorous clinical trial validation

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