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(2017) reported that this AChE inhibitory activity is associated with FSE-mediated activation of the Akt/GSK3 pathway, which also led to ameliorated memory and learning difficulties, Al toxicity, AChE hyperactivity, amyloid (A) aggregation, and apoptosis, in rats with AD-like AlCl3induced memory loss in this study

It is conceivable that KD could also increase glutaminolysis, another ATPgenerating pathway used by T cells (Wang et al , 2011

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On the other hand, it must be stressed that the above values are averages and there might be significant spatial heterogeneity 57

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