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With the development of imaging diagnosis technology, earlier and smaller breast cancers can be diagnosed early through advanced imaging tools, and the five-year survival rate of breast cancer has improved in the past decades [2, 3]

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Lactobacillus acidophilus inhibits bone loss and increases bone heterogeneity in osteoporotic mice via modulating Treg-Th17 cell balance

136 CancelloGMaisonneuvePRotmenszNVialeGMastropasquaMGPruneriGet al

32 Concurrently, energy deficiency contributes to an ionic imbalance that affects Na + , K + , and Ca 2+ levels, leading to cell depolarization and prompting glutamate release