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Supplementation with Pycnogenol helped promote healthy blood pressure levels, with statistically significant reductions in markers of blood vessel constriction

The activity of hexokinase, a crucial rate-limiting enzyme in glycolysis, significantly decreased, and the levels of NADH, NAD + , and ATP within the cells markedly dropped in a concentration-dependent manner (Figure 8C)

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When focusing on CD38-driven immunometabolic changes within APP carriers, CD38-expressing T cells exhibited increased CD39 and KLRG1 expression (Supplementary Fig