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Efficacy-wise, AOD-9604 produces modest results (2-3 kg over 12 weeks in trials) compared to GLP-1 agonists dramatic weight loss

The reduction in red blood cell production is why patients with B12 deficiency report feeling so extremely fatigued (even under the slightest of efforts), sort of like the fatigue you get from altitude sickness

Implications for Health and Lifespan Improving healthspan is directly associated with a decrease in cellular senescence, which presents the prospect of increasing life expectancy rather than merely life expectancy

By increasing energy levels, enhancing metabolism, reducing appetite, and even improving mood, B12 injections work to address some of the most common challenges individuals face on their weight loss journey

Allow 2-4 weeks to assess tolerance before increasing

MTHFR deficiencies lead to a shortage of the active form of folate within the body and negatively impacts the conversion of homocysteine to methionine