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Furthermore, the authors reported subtle differences in I hERG stimulation depending on LCAC chain length ( I hERG blockade in Langendorff-perfused guinea pig hearts failed to prevent LCAC-dependent mechanical dysfunction ( + currents, including the transient outward K + current ( I to ) ( + current ( I K,ATP ) ( I K,ATP lipid gating ( Summary of LCAC Effects on Cardiac Excitation-Contraction Coupling The electrical and mechanical alterations to cardiac muscle induced by LCAC exposure can be attributed to a pleiotropy of modulations in ECC mechanisms

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