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Rollin SPG, Lawrence MG, Joshua AM, Selth LA Friend or foe

PK, receptor, prokineticin receptor

Multiple preclinical and clinical studies showed that epigenetic mechanisms are involved in the pathophysiology and treatment of stress-related depressive and cognitive disorders

The TRP-KYN Pathway and the Nervous System Besides TRP, some kynurenines, such as KYN, 3-HKYN, and ANA, primarily of hepatic and intestinal microbiota origin, cross the BBB and enter the TRP-KYN pathway