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A patient with a serious non-healing musculoskeletal injury, conventional options exhausted, full informed consent, ideally inside a registered investigational protocol with structured safety monitoring

Individual Response: Peptides can have variable effects from person to person

161 ZhangY.XiaM.JinK.WangS.WeiH.FanC.et al (2018c)

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The peptide influences both endothelial nitric oxide synthase (eNOS), which produces the beneficial, vasodilating form of nitric oxide, and inducible nitric oxide synthase (iNOS), which can produce excessive amounts that contribute to inflammation and tissue damage