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LL-37 offers strong antimicrobial and immunomodulatory effects critical for infected wounds, enhancing tissue repair and angiogenesis [88]

BMJ Open 11(9):e047831, 2021

Commercial payers often apply stricter coverage criteria than Medicare for off-label drug use

EC inhibited p-p65 nuclear expression and suppressed NLRP3 inflammasome activation, resulting in decreased cytokine production and macrophage infiltration in inflamed synovial tissues