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doi: 10.1016/j.redox.2023.103007

Chloroquine, a FDA-approved drug, prevents Zika virus infection and its associated congenital microcephaly in mice

In addition, in an environment of chronic nitro-oxidative stress, mTOR may be inactivated by oxidation of Cys1483 [449] and AMPK activation [450, 451]

that looked at oral versus intramuscular administration: In oral/sublingual replacement therapy, it is administered daily, while intramuscular administration follows weekly and then monthly patterns (or daily/weekly/monthly depending on the protocol and case)