clozapine glutathione adduct Detection of Reactive Metabolites Using Isotope-Labeled Trapping and Simultaneous Neutral Loss and Precursor Ion Scanning with Ultra-High-Pressure Liquid Chromatography Triple Quadruple Mass Spectrometry Full article: Therapeutic drug monitoring
Full article: Therapeutic drug monitoring of clozapine in adults with schizophrenia: a review of challenges and strategies Identification and quantification of glutathione adducts of clozapine using ultrahighperformance liquid chromatography with orthogonal acceleration timeofflight mass spectrometry and inductively coupled plasma mass spectrometry MacDonald 2011 Predicting hepatotoxicity: Reactive metabolite trapping using glutathione and freshly isolated hepatocytes Technology Networks Role of Human Glutathione S Transferases in the Inactivation of Reactive Metabolites of Clozapine Chemical Research in Toxicology A highthroughput glutathione trapping assay with combined high sensitivity and specificity in highresolution mass spectrometry by applying product ion extraction and datadependent neutral loss Wang 2019 Journal of Mass A novel quantitative assessment of formed reactive metabolites by double trapping with [3H]glutathione and [14C]cyanide ScienceDirect
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