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Mastrangelo et al

Acta 104 QiW

Active site residues U46, L48, Q81, and W136 are highlighted and shown as sticks

Similar content being viewed by others Background l-glutathione (-glutamyl-l-cysteinylglycine, GSH) is a tripeptide that is the most abundant non-protein thiol in animals, plants, and microorganisms [1]

2 Pathological role of ferroptosis in retinal diseases The retina is mainly composed of the inside out of retinal pigment epithelial cells (RPE), photoreceptor cells, horizontal cells, bipolar cells, node cells, amacrine cells, and retinal ganglion cells (RGC), as the key part of the vision with the functions that captures light and passes it to the brain (Hoon et al., 2014)

Contraction of resident macrophage populations has been reported in inflammatory conditions such as myocardial infarction 44 and infection 48 due to largely unexplored reasons