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doi: 10.1016/j.fitote.2013.11.011 18 MaQ-JHanLMuYGuanP-PLeiHWangZ-Yet al

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The oligomerization and activity of recombinant NFU1 has not yet been tested in vitro

Therapeutic peptides are synthetic versions of these natural compounds, designed to amplify specific repair and recovery signals

Current therapies under investigation (Table 8) are targeting muscle-specific kinase (MuSK), which promotes post-synaptic clustering, synaptogenesis via F-actin branching and dendritic proliferation [293], and reduction of aberrant sphingolipid regulation to promote NMJ stability [294]