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Harris LA, Saad H, Shelton KE, Zhu L, Guo X, Mitchell DA

[DOI] [PMC free article] [PubMed] [Google Scholar] Charlton M., Krishnan A., Viker K., Sanderson S., Cazanave S., McConico A., Masuoko H., Gores G

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The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy

Chemotherapy is a pivotal modality in cancer treatment, yet its efficacy is severely hindered by the pervasive challenge of resistance 40,41

This autophosphorylation event serves as the first signal that propagates through multiple intracellular pathways