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(See also point 3 and 4, note 2) Supplementation (1000 mcg hydro(xo)cobalamine B12 injections, 2 times a week intramuscularly or deep subcutaneously for five weeks, or once a week for ten weeks) is primarily done when deficiency has been diagnosed

Specific Adverse Effects Reported in Clinical Trials While the overall safety profile was excellent, clinical trials documented all adverse events regardless of severity or causality

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Injection site reactions: Pain, local tenderness , or swelling at the site of injection

Cyanocobalamin is a synthetic form commonly used in lower-cost supplements

Patients should always follow the prescription label and instructions from their licensed healthcare provider