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Gamma-glutamyl transpeptidase: Redox regulation and drug resistance

doi: 10.1523/JNEUROSCI.0979-11.2011 82 LinnstaedtS

Vitamin A (Beta-Carotene, Retinol) Vision, skin health, and oxidative balance supporter While primarily known for its role in vision, vitamin A and its precursors (carotenoids) also function as antioxidants: Beta-carotene and other carotenoids efficiently quench singlet oxygen, a reactive oxygen species particularly damaging to the skin and eyes Retinol helps maintain epithelial tissue integrity, providing a first-line defense against oxidative stressors Carotenoids like lutein and zeaxanthin specifically protect the retina from oxidative damage Vitamin A supports immune function, helping prevent inflammation-induced oxidative stress Unlike other antioxidants, vitamin A can be toxic at high doses, requiring careful supplementation

Immunol Cell Biol 80:550557 Kim SM, Ha JS, Han AR, Cho SW, Yang SJ (2019) Effects of -lipoic acid on LPS-induced neuroinflammation and NLRP3 inflammasome activation through the regulation of BV-2 microglial cells activation

The recovery process generally follows a predictable pattern, though individual variation is common