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In mitochondria, the catalytic conversion is carried out by methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) or its homolog MTHFD2-like (MTHFD2L), mitochondrial enzymes harboring both methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities

Figure 1 shows the most significant differences observed in the signals of the spectra at T1 compared to those at T0: the variations in concentration are indicated as log 2 (fold change)

Primary effusion lymphoma Kaposis sarcoma-associated herpesvirus (KSHV) is the etiologic agent of primary effusion lymphoma (PEL), which comprises transformed B cells harboring the viral episome and arises preferentially within the pleural or peritoneal cavities of patients infected with HIV [35]

doi: 10.1111/febs.16164

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Taken together, these findings indicate that nanoalgosome pre-exposure significantly mitigates intracellular ROS generation in response to TBHP-induced oxidative stress