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The functionality of this prototype was evaluated by 1) visual evaluation of the generated plasma spots ensuring that the 3D card is capable of producing hemolysis-free plasma spots and 2) automated on-line analysis using the previously validated DPS-SPE-LC-ESI-MS/MS (dried plasma spot-solid phase extractionliquid chromatography-electrospray ionizationtandem Mass Spectrometry) method for quantitative determination of hydrocodone using deuterium-labeled internal standard

Barros, MA et al (2015)

Acid-sensing ion channel 1a-mediated calcium influx regulates apoptosis of endplate chondrocytes in intervertebral discs

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For example, ribavirin, dissolved in PBS at 100 mg/ml at 50C, was encapsulated in liposomes consisting of DPPC (55%), cholesterol (41%), rhodamine-PE (0.04%) and mPEG-DSPE (4.4%), dissolved in 2-propanol, using an emulsifier (Emulsiflex-C3)

Compared to the group with the lowest amount, the group with the second highest amount of acetaminophen was 2.14 times more likely to have ASD, while the group with the highest amount was 3.62 times more likely to have ASD