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This review was supported by grants from the Wu Jieping Medical Foundation Research Special Project (no

GHK-Cu + Vitamin C & Zinc Research protocols commonly investigate GHK-Cu alongside: Vitamin C Zinc because of their involvement in: Collagen-related pathways Skin-integrity and dermal-maintenance mechanisms Antioxidant-support pathways Tissue-maintenance and regenerative signaling Physiological-resilience pathways Vitamin C is commonly investigated for its interaction with collagen-support and antioxidant-related pathways, while Zinc is frequently researched for its role in skin-integrity, tissue-maintenance, and copper/zinc balance within GHK-Curelated research models

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Subsequently, t-distributed stochastic neighbor embedding (t-SNE) dimensionality reduction was conducted on the top 10 principal components using the RunTSNE function

Small sample sizes, absent control groups, and publication bias mean these results could overestimate true effects