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As lesions advance, substantial extracellular lipid accumulates in the core, in part due to large CE-rich particles arising from dead macrophage foam cells (149,150)

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Immunohistochemistry Paraffin sections of synovial tissues were deparaffinized, rehydrated in descending grades of ethanol, preincubated with BSA for 10 min, and then treated in cold storage overnight with primary antibody (CPT1

The body weight, food intake, and tumor size were measured every other day