Disclosures: Farzaneh Tamnanloo: Nothing to Disclose, Quang Toan Pham: Nothing to Disclose, Marie-Agns MCallum: Nothing to Disclose, Denis Cyr: Nothing to Disclose, Paula Waters: Nothing to Disclose, Emilie Beaulieu: Nothing to Disclose, Yannick Doyon: Nothing to Disclose, Ugur Halac: Nothing to Disclose, Claudia Raggi: Nothing to Disclose, Massimiliano Paganelli: Morphocell Technologies: Executive role 2500 THE RELATIONSHIP BETWEEN SERUM BILE ACIDS AND EVENT-FREE SURVIVAL FOLLOWING THE USE OF MARALIXIBAT FOR PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS: DATA FROM MARCH/MARCH-ON Richard Thompson 1 Lorenzo D'Antiga 2 Simon Horslen 3 Douglas Mogul 4 Tiago Nunes 4 Will Garner 4 Pamela Vig 4 Alexander Miethke 5 , 1 King's College London, United Kingdom, 2 Papa Giovanni XXIII, Bergamo, Italy, 3 UPMC Children's Hospital of Pittsburgh, Pennsylvania, 4 Mirum Pharmaceuticals, Inc., Foster City, California, 5 Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio Background: Maralixibat, an inhibitor of the ileal bile acid transporter, is approved in the US for treatment of cholestatic pruritus in individuals 3 months with Alagille Syndrome (ALGS) and 5 years with Progressive Familial Intrahepatic Cholestasis (PFIC)
Eggs, beef, fish, chicken and nuts represent dietary sources of choline (Derbyshire, 2019), individuals on a gluten-free or vegan restricted diet may also wish to consider pseudocereals amaranth, buckwheat and quinoa as alternative dietary sources for betaine (Ross et al, 2014)
Warnings Please be aware that this product carries potential risks, as is the case with all peptide compounds
6.6.7 Adipokines IBD is distinguished by symptoms such as reduced appetite, inadequate nutrition, changes in body composition, and the enlargement of mesenteric white adipose tissue (mWAT) (285, 286)
doi: 10.3389/fimmu.2021.762315 35 BradleyD
L-Theanine also attenuates the release of cortisol in response to stress, helping to maintain a balanced stress response
