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These effects were not reproduced in 3-AR knockout mice, suggesting that the 3-AR plays a key role in the compounds chronic metabolic effects (Heffernan et al

Upregulation of SIRT3 contributes to myocardial protective effect of PGC1

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The jump from 4mg to 8mg added another 5.7 percentage points, reaching 22.8%

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Whilst there is also evidence that sulforaphane reduces cancer development, future research on the underlying molecular mechanisms is also warranted to further understand the role of sulforaphane in the metabolic rewiring of cancer progression