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(The discovery) has boosted interest since the death of the cell is induced by its own iron content (which damages cell membranes)

Effect of sesquiterpene lactones on antioxidant enzymes and some drug-metabolizing enzymes in rat liver and kidney

However, the clinical relevance of its effects is currently unclear, given the limitations of the studies identified, including the heterogeneity of studies, the number of studies with insufficient power, and other methodologic considerations [100]