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Collectively, organ age gap associations with disease and blood biochemistry demonstrate that aging models derived from organ-specific plasma proteins capture disease-relevant heterogeneity of aging within and across individuals, which is not captured by other aging clocks or clinical markers

GPX4 was a significant prognostic factor for OS and DFS on multivariate analysis at both 5% and 25% cutoff values

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Additionally, insecticidal cyclotides such as kalata B1 and kalata B2 target the physiological integrity of insect midgut cells

Molecular docking The CNMT PDB structure file was downloaded from the Uniprot database and modified in Chimera (UCSF) 66