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In addition, erastin or RSL3, which are classical ferroptosis activators, can cause abundant intracellular iron ion accumulation and thus inhibit the intracellular antioxidant system and then increase damage caused by oxidation by generating ROS through the Fenton reaction

[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Wan MJ, su XY, Zheng Y, et al

K.SuzukiK.TingJ

4.3 DNA damage detection DNA damage is one of the major consequences of oxidative stress, including base modifications, strand breaks, and base loss

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