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Resistance Fold was calculated by dividing the IC 50 value of a substrate drug into drug-resistant KB/CV60 cells in the presence or absence of an inhibitor (sertraline, fluoxetine, citalopram, or ONO-1078) by the IC 50 value of parental KB-3-1 cells without an inhibitor

Pharmacometabolomics of Response to Sertraline and to Placebo in Major Depressive Disorder Possible Role for Methoxyindole Pathway

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If the process of oxidation is not reversed at this stage, further oxidation results in the formation of irreversibly oxidized products such as sulfinic and sulfonic acids (Fig

Xie B, Lin J, Chen X, Zhou X, Zhang Y, Fan M, et al

Interferon regulatory factor 3, also known as IRF3, is activated when these two proteins go through the process of dimerization, which ultimately results in the release and production of interferon beta, also known as IFN- (Duan et al